Diosmin
Xi'an Rainbow Bio-Tech Co., Ltd 
【NAME】：Diosmin
【SYNONYMS】：BAROSMIN
【SPEC.】：EP5 EP6
【TEST METHOD】： HPLC
【PLANT SOURCE】：citrus aurantium l.
【CAS NO.】：520-27-4
【MOLECULAR FORMULAR & MOLECULAR MASS】：C28H32O15 608.54
【STRUCTURE FORMULA】： 
【CHARACTERISTIC】：Greyish-yellow or light yellow hygroscopic powder. It dissolves in dilute solutions of alkali hydroxides. Almost insoluble in water, soluble in DMSO, almost insoluble in ethanol, soluble in dilute alkaline solution.
【PHARMACOLOGY】：Treatment of venous lymphatic insufficiency associated symptoms (heavy legs, pain, discomfort, soreness early morning) - the treatment of acute hemorrhoid attack on a variety of symptoms. With vitamin P-like effects, can reduce vascular fragility and abnormal permeability, but also for the control of the adjuvant treatment of hypertension and arteriosclerosis, for the treatment of capillary fragility was better than rutin, hesperidin and stronger, and has low toxicity characteristics. Of the vein system to play its active role in: - reduce venous distensibility and venous stasis zone. - In the micro-circulatory system, so that the normalization of capillary wall permeability and increase their resistance.
【CHEMICAL ANALYSIS】
|
ITEMS |
RESULTS |
| Assay(HPLC),anhydroussubstance(2.2.29) |
90%--102% |
| Residual Solvents(2.4.24) -Methanol -Ethanol -Pyridine |
≤3000ppm ≤0.5% ≤200ppm |
| Iodine(2.2.36)&(2.5.10) : Related substances (HPLC)(2..2.29) Impurity A: acetoisovanillone Impurity B: hesperidin Impurity C: isorhoifin Impurity E: linarin Impurity F: diosmitin Others impuritys Total others impuritys and impurity A Total impuritys Heavy metals (2.4.8) Water(2.5.12) Sulphated ash(2.4.14) |
≤0.1% ≤1.0% ≤5.0% ≤3.0% ≤3.0% ≤3.0% ≤1.0% ≤1.0% ≤10.0% 20ppm ≤6.0% ≤0.2% |
【PACKAGE】：Packed in paper-drums and two plastic-bags inside.N.W.:25kgs .
【STORAGE】：Keep in cool, dry and dark place, avoid high temperature.
【SHELF LIFE】：24 months |
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